In a groundbreaking study published in Nature Aging, researchers have identified a combination of interventions that may significantly slow the biological aging process and reduce the risk of invasive cancers. The study, known as the DO-HEALTH trial, involved nearly 800 healthy adults aged 70 and older across five European countries.
Key Findings:
• Omega-3 Supplementation: Participants who consumed one gram of omega-3 fatty acids daily for three years exhibited a biological aging process that was approximately three months slower than those who did not.
• Combined Interventions: The most significant benefits were observed in participants who combined omega-3 supplementation with 2,000 IU of vitamin D daily and engaged in regular exercise. This group experienced a biological aging slowdown of about four months over the three-year period and a 61% reduction in the risk of invasive cancer.
The study utilized epigenetic clocks to assess DNA methylation markers, providing insights into biological age beyond chronological measurements. Additionally, participants following the combined regimen reported fewer falls, infections, and instances of pre-frailty, indicating broader health benefits.
Implications:
These findings suggest that accessible interventions like omega-3 and vitamin D supplementation, alongside regular physical activity, can contribute to healthier aging. However, researchers emphasize the need for further studies to confirm these results and to explore the long-term impact on lifespan and overall healthspan.
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Disclaimer: Always consult with a healthcare professional before starting any new supplement regimen.